What is HIV?
HIV stands for Human Immunodeficiency Virus. HIV is the virus that causes AIDS.
While many viruses can be controlled by the immune system, HIV targets and infects the same immune system cells that are supposed to protect us from illnesses. These are a type of white blood cell called CD4 cells. HIV takes over CD4 cells and turns them into virus factories that produce thousands of viral copies. As the virus grows, it damages or kills CD4 cells, weakening the immune system.
What is AIDS?
AIDS stands for Acquired Immune Deficiency Syndrome. AIDS is the most advanced stage of HIV infection. HIV causes AIDS by attacking the immune system’s soldiers – the CD4 cells. When the immune system loses too many CD4 cells, you are less able to fight off infection and can develop serious, often deadly, infections. These are called opportunistic infections (OIs) because they take advantage of the body's weakened defenses.
When someone dies of AIDS, it is usually opportunistic infections or other long-term effects of HIV infection that cause death. AIDS refers to the body’s immune-compromised state that can no longer stop OIs from developing and becoming so deadly.
What is the Difference Between HIV and AIDS?
You don't have AIDS as soon as you are infected with HIV. You can be HIV+ for many years with no signs of disease, or only mild-to-moderate symptoms. But without treatment, HIV will eventually wear down the immune system in most people to the point that they develop more serious OIs.
The Centers for Disease Control and Prevention (CDC) defines someone as having AIDS if he or she is HIV+ and meets one or both of these conditions:
- Has had at least one of 21 AIDS-defining opportunistic infections
- Has had a CD4 cell count (T-cell count) of 200 cells or less (a normal CD4 count varies by laboratory, but usually is in the 600 to 1,500 range)
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